The Journal of the National Cancer Institute has published a new GenoMEL paper examining the role of chromosomal telomere length in melanoma. The research involved creating a score representing genetically determined telomere length, based on all the established telomere associated genes and found that this score correlated with melanoma risk.
In an associated press release author Dr Mark Iles summarised the research, “Telomeres have been described as being like the plastic tips on shoelaces that protect the shoelace from fraying, just as telomeres protect chromosomes from degrading or fusing to one another. For the first time, we have established that the genes controlling the length of these telomeres play a part in the risk of developing melanoma.”
Telomeres are akin to shoe lace caps (aglets)