Geoff Walker recently completed Ironman France and asked for sponsorship in memory of a dear friend, Bernie Jackson, who died from melanoma earlier this year. The challenge involved over 140 miles of swimming, biking and running and Geoff has raised over £2,000 to support GenoMEL’s research. Donations are still being accepted at JustGiving.com Congratulations to Geoff and thank you to all his sponsors.
A GenoMEL study of somatic BRAF and NRAS mutations in familial melanomas with known germline CDKN2A status has been published in the Journal of Investigative Dermatology. This study set out to investigate whether inheriting a CDKN2Amutation influences the mutations found within the actual tumour. Led by researchers in Sweden, it involved colleagues from more than eight different research groups and samples from over 100 patients.
The 2013 meeting in Philadelphia was a great success. As well as pleasing progress with existing projects, several new initiatives and grant awards were announced. The meeting also featured GenoMEL’s first remote presentation, with Dr Nadine Kasparian presenting from Sydney, Australia 9,000 miles away. We are very grateful to the Abramson Cancer Center and the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania for their support.
Dr. Eduardo Nagore from the Valencia Institute of Oncology has kindly offered to host the 2014 meeting in Valencia, Spain. Dates to be announced!
World spanning research*
A new GenoMEL paper is available from the Nature Genetics website entitled, ‘A variant in FTO shows association with melanoma risk not due to BMI’. Some variations in the FTO gene have been linked to obesity, but this is the first study to link FTO variations with melanoma. This was a global study of more than 13,000 melanoma patients and a huge collaborative effort.
A University of Leeds
press release is available.
*Image courtesy of posterize at FreeDigitalPhotos.net
A new Journal of Medical Genetics paper from GenoMEL is available online. It reports an international study of all known families with rare germline mutations in the CDK4 gene, led by Professor Anders Molven from the University of Bergen in Norway. This open access paper is an impressive achievement, involving numerous collaborators. It is available from the journal’s website.