Lund Melanoma Study Group
Håkan Olsson MD PHD
Christian Ingvar, MD PhD
Åke Borg MD PhD
The melanoma group in Lund is directed towards understanding the genetic and environmental epidemiology of susceptibility to melanoma and its tumour biology and prognosis. The multidisciplinary group, that involves oncologists, surgeons, dermatologist, statistician, pathologists, and molecular biologist, has investigated among other things the role of constitutional factors (hair colour, eye colour, freckling, number of nevi), sun exposure, other sources of UV exposure (sunbeds) and genetic factors of melanoma. The Swedish founder mutation, ins 113 Arg, was first described by our group. Large case control and cohorts studies as well as biobanks of blood and tumour tissue makes a strong foundation for ongoing and future studies. Regurlarly this information is linked to data from population based registries such as Cancer Registry data and Cause of Death Registry data. A large number of families with familial/hereditary melanoma have been collected and special groups as patients with multiple tumours and ocular melanomas are the scope of present studies.
The names and e-mail addresses of group members with a description of their contribution
Anna Måsbäck MD PhD
Kari Nielsen MD
Nils Jonsson MD PhD
Lotta Lundgren MD PhD
Johan Westerdahl MD PhD
Göran Jönsson PhD
Anita Smith Casslen
Westerdahl J, Olsson H, Måsbäck A, Ingvar C, Jonsson N, Brandt L, et al.
The use of sunbeds/sunlamps and malignant melanoma in southern Sweden.
Am J Epidemiol 1994;140:691-696.
Borg Å, Johannsson O, Westerdahl J, Måsbäck A, Olsson H, Ingvar C.
Novel germline mutation in the p16/CDKN2/MTS1 gene in familial malignant melanoma in south Sweden.
Cancer Research 1996;56(June 1):2497-2500.
Borg Å, Sandberg T, Nilsson K, Johanssson O, Klinker M, Måsbäck A, et al.
High frequency of multiple melanoma, breast and pancreas cancer in CDKN2 mutation positive families.
Nielsen K, Ingvar C, Måsbäck A, Westerdahl J, Borg Å, Sandberg T, Olsson H.
Melanoma and non-melanoma skin cancer in patients with four or more tumours – a population based study.
Br J Dermatology 2004;150 (3)(March):531-536.
Westerdahl J, Måsbäck A, Ingvar C, Olsson H.
Sunscreen use and malignant melanoma.
Int J Cancer 2000;87:145-150.
Jönsson G, Bendahl PO, Sandberg T, Kurbasic A, Staaf J, Sunde L, Cruger D, Ingvar C, Olsson H, Borg Å.
Mapping of a novel ocular and cutaneous malignant melanoma susceptibiligy locus to chromosome 9q21.32.
Journal of the National Cancer Institute 1005; 97; 1377-1388.